Pavana M Hegde Selected Research

5-hydroxyuracil

9/2010

Specific Inhibition of NEIL-initiated repair of oxidized base damage in human genome by copper and iron: potential etiological linkage to neurodegenerative diseases.

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Pavana M Hegde Research Topics

Disease

7	Neurodegenerative Diseases (Neurodegenerative Disease) 03/2024 - 09/2010
6	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 03/2024 - 11/2018
3	Mitochondrial Diseases (Mitochondrial Disease) 03/2024 - 01/2020
3	Motor Neuron Disease (Primary Lateral Sclerosis) 03/2024 - 10/2016
3	Sarcoma (Soft Tissue Sarcoma) 03/2024 - 10/2016
3	Parkinson Disease (Parkinson's Disease) 01/2020 - 09/2010
3	Neoplasms (Cancer) 07/2017 - 11/2012
2	Machado-Joseph Disease (Spinocerebellar Ataxia Type 3) 01/2024 - 01/2015
2	Genomic Instability 01/2020 - 01/2019
2	Disease Progression 11/2018 - 10/2016
1	Hemorrhage 01/2020
1	Cerebral Hemorrhage 01/2020
1	Ataxia Telangiectasia (Louis Bar Syndrome) 01/2019
1	Carcinogenesis 07/2017
1	Chromosomal Instability (Chromosome Stability) 07/2017
1	Liposarcoma 10/2016
1	Stroke (Strokes) 01/2014
1	Wounds and Injuries (Trauma) 01/2014
1	Lung Neoplasms (Lung Cancer) 06/2012
1	Alzheimer Disease (Alzheimer's Disease) 09/2010
1	Neuroblastoma 09/2010

Drug/Important Bio-Agent (IBA)

8	DNA (Deoxyribonucleic Acid)IBA 01/2024 - 06/2012
4	IronIBA 01/2020 - 09/2010
3	Proteins (Proteins, Gene)FDA Link 08/2015 - 11/2012
3	CopperIBA 07/2014 - 09/2010
2	Mitochondrial DNA (mtDNA)IBA 03/2024 - 07/2023
2	Polynucleotide 5'-Hydroxyl-Kinase (Kinase, Polynucleotide)IBA 01/2024 - 01/2015
2	EnzymesIBA 01/2024 - 01/2015
2	SynucleinsIBA 01/2020 - 01/2017
2	alpha-SynucleinIBA 01/2020 - 01/2017
2	Ligases (Synthetase)IBA 09/2019 - 01/2019
2	DNA-Binding Proteins (DNA Binding Protein)IBA 01/2019 - 10/2016
2	RNA (Ribonucleic Acid)IBA 01/2019 - 10/2016
2	DNA Glycosylases (DNA Glycosylase)IBA 07/2014 - 06/2012
2	MetalsIBA 01/2014 - 01/2011
1	CarbonIBA 01/2020
1	Hemin (Panhematin)FDA Link 01/2020
1	Amyloidogenic ProteinsIBA 01/2020
1	1,2- di- (4- sulfamidophenyl)- 4- butylpyrazolidine- 3,5- dione (DSB)IBA 01/2019
1	Monomeric GTP-Binding ProteinsIBA 01/2019
1	ChromatinIBA 01/2017
1	Ataxin-3IBA 01/2015
1	polyglutamineIBA 01/2015
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2014
1	Chelating AgentsIBA 01/2011
1	CytosineIBA 09/2010
1	5-hydroxyuracilIBA 09/2010
1	Cell ExtractsIBA 09/2010
1	DNA-(Apurinic or Apyrimidinic Site) Lyase (AP Endonuclease)IBA 09/2010

Therapy/Procedure

4	Therapeutics 01/2020 - 07/2017
1	Ligation 11/2018
1	Radiotherapy 11/2012